The correct statement about cystic fibrosis is:
Cystic fibrosis is caused by a deletion mutation.
Cystic fibrosis is indeed caused by specific genetic mutations in the CFTR gene, including a common deletion of three bases that leads to the loss of a phenylalanine amino acid. The other options are incorrect: cystic fibrosis affects both men and women, it is not a silent disorder since it has various symptoms, and there is a well-understood genetic basis for its occurrence.