Cystic fibrosis is an inherited disorder that is caused when three bases are accidentally removed from the CFTR gene. Which of the following is true about cystic fibrosis?(1 point)

Question

Responses

Cystic fibrosis is a silent disorder, it has no symptoms.
Cystic fibrosis is a silent disorder, it has no symptoms.

It is not known why cystic fibrosis happens in people.
It is not known why cystic fibrosis happens in people.

The affects of cystic fibrosis only impact women.
The affects of cystic fibrosis only impact women.

Cystic fibrosis is caused by a deletion mutation.

Answer 1

The correct response is:

Cystic fibrosis is caused by a deletion mutation.

Cystic fibrosis is indeed caused by a deletion mutation in the CFTR gene, specifically the deletion of three nucleotide bases which results in the loss of a phenylalanine amino acid at position 508 of the protein. This mutation disrupts the normal function of the CFTR protein that regulates salt and water balance in epithelial tissues.