Question

You wish to measure the ∆G°' for the hydrolysis of ATP:

ATP --->ADP + Pi

But the equilibrium for the hydrolysis lies so far toward products that analysis of the ATP concentration at equilibrium is neither practical or accurate. However, you have the following data that will allow calculation of the value indirectly.

K'eq = 59.5
∆G°' = +43.0 kJ/mole

Reaction 1:Creatine phosphate+ADP->ATP + creatine

Reaction 2:Creatine+Pi -> creatine phosphate

a) Calculate the ∆G°' for rxn. 1

b) Calculate the ∆G°' for the hydrolysis of ATP

I really need help with the steps to this problem, thank you!!