Which statement about cystic fibrosis is true?(1 point)

Question

Responses

Cystic fibrosis is caused by a deletion of one codon in the DNA molecule.
Cystic fibrosis is caused by a deletion of one codon in the DNA molecule.
Carriers have an advantage over people who do not have the cystic fibrosis mutation.
Carriers have an advantage over people who do not have the cystic fibrosis mutation.
Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele.
Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele.
Cystic fibrosis affects a person's ability to make normal red blood cells.

Answer 1

The correct statement about cystic fibrosis is:

Carriers have an advantage over people who do not have the cystic fibrosis mutation.

Cystic fibrosis (CF) is caused by mutations in the CFTR gene, most commonly a deletion of three nucleotides that results in the loss of the amino acid phenylalanine at position 508 (ΔF508), not a deletion of a whole codon. Individuals who are carriers (having one copy of the mutated gene) may have some protection against certain infections like cholera or typhoid fever, which historically provided a selective advantage.

The other statements provided are not accurate regarding cystic fibrosis.