The statement that is true regarding cystic fibrosis is:
Carriers have an advantage over people who do not have the cystic fibrosis mutation.
Carriers of one copy of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation may have a selective advantage in certain environments, particularly against severe forms of diarrhea caused by pathogens like cholera. However, other statements in your list regarding the causes of cystic fibrosis and its effects on red blood cells are incorrect. Cystic fibrosis is caused by mutations in the CFTR gene, and it does not affect red blood cells. It is also a recessive disorder, not caused by a dominant allele replacing a recessive one. The most common mutation associated with cystic fibrosis is a deletion of three nucleotides, which affects the production of the CFTR protein.