Which statement about cystic fibrosis is true?(1 point)

Responses

Cystic fibrosis affects a person's ability to make normal red blood cells.
Cystic fibrosis affects a person's ability to make normal red blood cells.
Cystic fibrosis is caused by a deletion of one codon in the DNA molecule.
Cystic fibrosis is caused by a deletion of one codon in the DNA molecule.
Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele.
Cystic fibrosis is caused by a mutation in which a dominant allele replaces a recessive allele.
Carriers have an advantage over people who do not have the cystic fibrosis mutation.

1 answer

The statement that is true regarding cystic fibrosis is:

Carriers have an advantage over people who do not have the cystic fibrosis mutation.

Carriers of one copy of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation may have a selective advantage in certain environments, particularly against severe forms of diarrhea caused by pathogens like cholera. However, other statements in your list regarding the causes of cystic fibrosis and its effects on red blood cells are incorrect. Cystic fibrosis is caused by mutations in the CFTR gene, and it does not affect red blood cells. It is also a recessive disorder, not caused by a dominant allele replacing a recessive one. The most common mutation associated with cystic fibrosis is a deletion of three nucleotides, which affects the production of the CFTR protein.