The statement that best describes the impact of the Proclamation of 1763 is: "The Proclamation of 1763 created conflict between the British government and the colonists, who felt that the government was intruding in their affairs too much."
The Proclamation was issued after the French and Indian War to stabilize relations with Indigenous Americans by prohibiting colonists from settling west of the Appalachian Mountains. This restriction frustrated many colonists, who had hoped to expand into new territories, leading to growing resentment towards the British government.