The statement that best describes the impact of the Proclamation of 1763 is: "The Proclamation of 1763 created conflict between the British government and the colonists, who felt that the government was intruding in their affairs too much."
The Proclamation prohibited colonial settlement west of the Appalachian Mountains in an effort to stabilize relations with Indigenous Americans, but many colonists were frustrated by this restriction, feeling it limited their opportunities for expansion and land acquisition. This ultimately contributed to rising tensions between the colonists and the British government.