To simplify the expression \( 16^{1/4} \), we can consider the factorization of 16.
The correct option is:
D) \( 16 = 2 \cdot 2 \cdot 2 \cdot 2 \)
This option shows that 16 can be expressed as \( 2^4 \). When we apply the exponent \( \frac{1}{4} \):
\[ 16^{1/4} = (2^4)^{1/4} = 2^{(4 \cdot \frac{1}{4})} = 2^1 = 2 \]
This simplification is most straightforward when expressing 16 as \( 2^4 \).