To simplify the expression \( 16 \frac{1}{4} \), it helps to analyze the factors of 16. The options provided include different factorizations of 16:
- \( 16 = 4 \cdot 2 \cdot 2 \)
- \( 16 = 2 \cdot 2 \cdot 2 \cdot 2 \)
- \( 16 = 4 \cdot 4 \)
- \( 16 = 8 \cdot 8 \)
The factorization that might be most straightforward for simplification is \( 16 = 2 \cdot 2 \cdot 2 \cdot 2 \) (which shows that 16 is \( 2^4 \)) because using powers often facilitates simplification with bases.
However, any of these factorizations could be useful depending on the context of the simplification. If you'd like to find a specific factorization to help with your calculations, please provide more details about the simplification process you're aiming at.
In general, \( 16 = 2^4 \) might be the most helpful in a mathematical context where base and exponents are involved.