Among the proteins listed, rubisco is typically the largest. Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) is a key enzyme involved in the process of photosynthesis, and it is a relatively large protein compared to ribosomes, aquaporins, and hexokinase.
While ribosomes are complex structures that consist of proteins and ribosomal RNA, the protein components themselves (which are part of the ribosome) are not as large as the full rubisco enzyme. Aquaporins are membrane proteins that facilitate the transport of water and are generally smaller. Hexokinase is an enzyme involved in glycolysis but is also smaller than rubisco.
So, in summary, the largest protein among the ones listed is rubisco.
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