To investigate the influence of certain estrogen-responsive neurons on energy expenditure, biologist Stephanie Correa et al. treated female and male mice with either saline solution or clozapine-N4-oxide (CNO), which activates the neurons. Monitoring the activity levels of the mice by measuring how frequently the animals broke infrared beams crossing their enclosures, Correa et al. found that the mice in their study showed sex-specific differences in response to neuron activation: ______

Question

Which choice most effectively uses data from the graph to complete the assertion?
Choose 1 answer:
Choose 1 answer:
(Choice A) the four groups of mice differed greatly in their activity levels before treatment but showed identical activity levels at the end of the monitoring period.
A
the four groups of mice differed greatly in their activity levels before treatment but showed identical activity levels at the end of the monitoring period.
(Choice B) CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.
B
CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.
(Choice C) saline-treated females showed substantially more activity at certain points in the monitoring period than saline-treated males did.
C
saline-treated females showed substantially more activity at certain points in the monitoring period than saline-treated males did.
(Choice D) CNO-treated females showed more activity relative to saline-treated females than CNO-treated males showed relative to saline-treated males.
D
CNO-treated females showed more activity relative to saline-treated females than CNO-treated males showed relative to saline-treated males.
which is the true correct answer a b c or d

Answer 1

To determine the most effective choice for completing the assertion about the sex-specific differences in the activity levels of mice in response to neuron activation, it is important to consider the details of the study and the results it reports.

• Choice A suggests that all groups ended up with identical activity levels after treatment, which does not convey a sex-specific difference.
• Choice B describes different patterns of activity response between CNO-treated females and CNO-treated males, indicating a clear sex difference in reaction to the treatment.
• Choice C refers to baseline activity differences between saline-treated females and males but does not address the response to neuron activation.
• Choice D compares the relative increases in activity between CNO-treated females and males compared to saline-treated groups, which is also relevant.

Given the need for sex-specific differences in activity in response to neuron activation, Choice B most effectively illustrates the distinct behavioral responses between female and male mice to the treatment, which seems to be the focus of the investigation.

Therefore, the correct answer is:

B - CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.