To effectively complete the assertion about the findings of Stephanie Correa et al. regarding the influence of estrogen-responsive neurons on energy expenditure in male and female mice, the answer should showcase the distinct activity patterns in response to treatment.
The most relevant choice that captures the sex-specific differences in the activity levels of the mice in response to neuron activation is:
(Choice B) CNO-treated females showed a substantial increase and then decline in activity over the monitoring period, whereas CNO-treated males showed a substantial decline in activity followed by a steep increase.
This choice highlights the differing reactions between the sexes when they were treated with CNO, demonstrating the impact of neuron activation on their activity levels.