The following table comes from a hypothetical case-control study that compared adults with moderate-to-severe acne (cases) to adults without acne (controls). The researchers examined the relationship between smoking and acne. The prevalence of moderate-to-severe acne in the population of interest is 35%.

Table 1. Adjusted odds ratios from logistic regression for moderate-to-severe acne. Odds ratios are adjusted for age, BMI, and alcohol consumption.
Variable Odds Ratio (95% CI)
Non-smoker (reference) 1.00
Ex-smoker 2.05 (1.02-4.23)
Current smoker 3.44 (0.98-6.46)
*p values <0.05.
How should we interpret the odds ratio of 3.44 for current smokers?

A) Current smokers have triple the risk of moderate-to-severe acne compared with non-smokers.
B) Current smokers have triple the risk of moderate-to-severe acne compared with ex-smokers.
C) Current smokers have no increase in the risk of moderate-to-severe acne, because the odds ratio is not statistically significant.
D) None of the above.
E) All of the above