Sickle cell anemia is caused by a substitution mutation. Specifically, it is a point mutation where adenine (A) is replaced by thymine (T) in the HBB gene, leading to the substitution of glutamic acid with valine in the hemoglobin protein. This change in the amino acid sequence is what causes red blood cells to become rigid and sickle-shaped.
sickle cell anemia What type of mutation error has occurred to cause the disorder shown?(1 point)
Responses
frameshift
frameshift
insertion
insertion
deletion
deletion
substitution
1 answer
1 answer