Question

Sequences for the types of hemoglobin are shown.



Sickle-cell anemia is caused by a mutation of one nucleotide in a gene. The type of mutation that causes sickle-cell anemia is known as

a
a frame-shift mutation.
b
an inversion mutation.
c
a point mutation.
d
an insertion mutation.

Answer 1

The type of mutation that causes sickle-cell anemia is known as **c. a point mutation**. This mutation involves the substitution of a single nucleotide in the DNA sequence, which leads to the production of an altered form of hemoglobin that causes red blood cells to become sickle-shaped.