Question

Question
Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3–5 sentences, summarize why this condition typically affects males more than females.

A chart shows the British hemophilia line.

(4 points)

Short Answer Rubric (4 points)
Points Awarded Criteria
4
The answer is very clear.

The answer is fully supported by details.

There may be a few errors in grammar, usage, or mechanics. Errors do not interfere with meaning.

3
The answer is mostly clear.

The answer is supported by mostly relevant details.

There are a few errors in grammar, usage, or mechanics. Errors do not interfere with meaning.

2
The answer is somewhat clear.

Details are weak or not related.

There are some errors in grammar, usage, and mechanics. Errors interfere with meaning.

1
The answer is not clear.

There are few or no supporting details.

There are many errors in grammar, usage, and mechanics. Errors interfere with meaning.

0 The question is not answered.

Answer 1

Hemophilia is a hereditary bleeding disorder that predominantly affects males due to its X-linked recessive inheritance pattern. Males have one X and one Y chromosome, meaning if their single X chromosome carries the mutated gene for hemophilia, they will express the condition. In contrast, females have two X chromosomes, so they can be carriers without showing symptoms if one of their X chromosomes has the normal gene. Therefore, hemophilia is more common in males, as they lack a second X chromosome that could potentially mask the effects of the defective gene.