Hemophilia is an X-linked recessive disorder, meaning the gene responsible for the condition is located on the X chromosome. Males have one X and one Y chromosome (XY), so if they inherit the affected X chromosome, they will express the disorder. In contrast, females have two X chromosomes (XX), so if they inherit one affected X chromosome, they typically have a second normal X chromosome that can compensate for the defective gene, making it less likely for them to express the disorder. This genetic mechanism is why hemophilia primarily affects males more than females.
Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3–5 sentences, summarize why this condition typically affects males more than females.
A chart shows the British hemophilia line.
(4 points)
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