Mefenamic acid (Ponstan Forte) has a half life of 2 hours.
Naproxen has a half life of 12 to 17 hours.
Both are anti inflammatory drugs of apparently similar nature but could someone please explain the difference in half life?
Thank you
Mike
1 answer
Absorbtion and breakdown are enzymatic reactions in the liver, "similar" is not good enough for many enzymes in reaction energy or speed. I would bet different enzyme pathways on breakdown.
1 answer