The statement that is MOST accurate regarding Mesosaurus fossils and continental drift is:
C. The Mesosaurus could not swim between the continents in the open ocean, so the fossils show that the continents must have been together in the past.
This statement highlights the fact that Mesosaurus was a freshwater reptile, and its presence in both South America and Africa suggests that the continents were once connected, allowing the species to inhabit these areas without the ability to cross vast oceanic distances.