How would you solve these problems? I am confused about what it is asking and how to start it. A step by step process with explanation would be greatly appreciated. Also, are there any simple ways to work out the problems without getting confused, or is there a way to know what methods to use to solve certain problems? Thank you.
1) A cross between two heterozygous organisms produces progeny with a phenotypic ratio of 253.65. Use a Chi square test to see if the data fits an expected 3:1 ratio. Do you accept or reject the data as fitting the ratio?
2) Cystic fibrosis is an autosomal recessive disorder. A male of unknown genotype (whose brother has the disease, but parents don't) has two children with a female of unknown genotype (whose sister has the disease, but parents don't), neither child has the disease. If they decide to have another child, what is the probAbility that the child will have the disease? Draw out the pedigrees.
3) In sesame, the one-pod condition (P) is dominant to the three-pod condition (p), and normal leaf (L) is dominant over wrinkled leaf (l). The two characters are inherited independently. A cross between two members of F1 generation produces the following progeny: 318 one-pod normal, 185 one-pod wrinkled, 323 three-pod normal and 184 three-pod wrinkled. Determine, using chi-square analysis whether the data fits the typical 9:3:3:1 ratio.
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