How would I scale down an experiment?

For example a procedure states that 5.0 g will be made (53% yield) but we want to propose a microscale procedure that would synthesize .120 g.

Do I simply divide desired amount of product by the one given in the procedure (.120/5) and take that ratio and multiply it to all reagents? Assuming the mole ratio is the same.

1 answer

Yes.
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