Asked by Joy
Here is the question:
If gene frequencies are in equilibrium, the genotypes, AA, Aa, and aa occur in a population with frequencies (1-0)^2, 20 (1-0), and 0^2. Plato et al.published the following data on haptoglobin type in a sample of 190 people:
Hp1-1 = 10
Hp1-2 = 68
Hp2-2 = 112
Test the goodness of fit of the data to the genetic model of this problem. Use Pearsons chi-square test. You may use the following information: the MLE estimator for 0 is 0^mle = 2X^3 + X^2 / 2n = 0.7684.
If gene frequencies are in equilibrium, the genotypes, AA, Aa, and aa occur in a population with frequencies (1-0)^2, 20 (1-0), and 0^2. Plato et al.published the following data on haptoglobin type in a sample of 190 people:
Hp1-1 = 10
Hp1-2 = 68
Hp2-2 = 112
Test the goodness of fit of the data to the genetic model of this problem. Use Pearsons chi-square test. You may use the following information: the MLE estimator for 0 is 0^mle = 2X^3 + X^2 / 2n = 0.7684.
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