Hemophilia is a sex-linked, recessive genetic disorder. Why are males more likely to be affected by the disorder than females?(1 point)

Responses

The mutation is found only on the Y chromosome, so it affects males more.
The mutation is found only on the Y chromosome, so it affects males more.
The mutation is found only on the Y chromosome, so females cannot get the disorder at all.
The mutation is found only on the Y chromosome, so females cannot get the disorder at all.
The mutation is found on the X chromosome, and since males only have one X chromosome, they only need one copy of the mutated gene to have the disorder.
The mutation is found on the X chromosome, and since males only have one X chromosome, they only need one copy of the mutated gene to have the disorder.
The mutation is found on the X chromosome, and since males have two X chromosomes, they are twice as likely to get the disorder.

1 answer

The correct response is:

The mutation is found on the X chromosome, and since males only have one X chromosome, they only need one copy of the mutated gene to have the disorder.

This is why males are more likely to be affected by hemophilia, as they have one X chromosome (XY), and if that X chromosome carries the mutated gene, they will manifest the disorder. In contrast, females have two X chromosomes (XX), so they would need two copies of the mutated gene to express the disorder, making it less likely for them to be affected.