Question

Hemophilia is a hereditary bleeding disorder that primarily affects males. Sunrise why this condition typically affects males more than females in 3 to 5 sentences.

Answer 1

Hemophilia is caused by a mutation in the genes responsible for blood clotting factors. These genes are located on the X chromosome. Males have one X chromosome and one Y chromosome, while females have two X chromosomes. Since the mutation is recessive, females can have one mutated and one normal X chromosome which usually provides enough clotting factors. On the other hand, males only have one X chromosome, so if it carries the mutation, they will be affected by hemophilia. Thus, males are more likely to have hemophilia than females.