Considering size-exclusion chromatography, ion-exchange chromatography, reversed-phase liquid chromatography, and capillary electrophoresis list the possible combinations (there are a total of 6) of techniques that could be coupled to give a 2-dimensional separation.

a. which technique of the two would be best suited as the 1st dimension
b. the orthogonality of the two techniques
c. the comprehensiveness of the combination

1 answer

a. which technique of the two would be best suited as the 1st dimension
b. the orthogonality of the two techniques
c. the comprehensiveness of the combination