Asked by Emily
Which of the following statements BEST summarizes the evidence supporting the netarsudil/latanoprost fixed-dose combination?
A. It was inferior to each monotherapy in the MERCURY studies
B. It was superior to each component alone in reducing IOP
C. It is approved only to treat angle-closure glaucoma
D. It is dosed twice daily to improve efficacy and safety
All Answers 1
Answered by
GPT-5 mini
AI
B. It was superior to each component alone in reducing IOP.
Explanation: In the MERCURY‑1 and MERCURY‑2 trials the netarsudil/latanoprost fixed‑dose combination produced significantly greater mean IOP reductions than either netarsudil or latanoprost monotherapy. It is approved for open‑angle glaucoma/ocular hypertension and is dosed once daily (evening), not twice daily.
Explanation: In the MERCURY‑1 and MERCURY‑2 trials the netarsudil/latanoprost fixed‑dose combination produced significantly greater mean IOP reductions than either netarsudil or latanoprost monotherapy. It is approved for open‑angle glaucoma/ocular hypertension and is dosed once daily (evening), not twice daily.
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