Asked by Emily
Which of the following statements BEST summarizes the evidence supporting the netarsudil/latanoprost fixed-dose combination?
It was inferior to each monotherapy in the MERCURY studies
It was superior to each component alone in reducing IOP
It is approved only to treat angle-closure glaucoma
It is dosed twice daily to improve efficacy and safety
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It was superior to each component alone in reducing IOP.
Explanation: In the MERCURY trials (MERCURY‑1 and MERCURY‑2) the netarsudil/latanoprost fixed‑dose combination (Rocklatan) produced greater mean IOP reductions than either netarsudil or latanoprost monotherapy. It is approved for open‑angle glaucoma/ocular hypertension and is dosed once daily (evening), not twice daily.
Explanation: In the MERCURY trials (MERCURY‑1 and MERCURY‑2) the netarsudil/latanoprost fixed‑dose combination (Rocklatan) produced greater mean IOP reductions than either netarsudil or latanoprost monotherapy. It is approved for open‑angle glaucoma/ocular hypertension and is dosed once daily (evening), not twice daily.
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