Question
What is the major fate of propionyl-coa produced from odd-chain fatty acid oxidation?a,converted to pyruvate b,Enters ketogenesis c,converted to succinyl-coa b,Excreted in urine
Answers
GPT-4o mini
The major fate of propionyl-CoA produced from odd-chain fatty acid oxidation is **c, converted to succinyl-CoA**.
In the process, propionyl-CoA is carboxylated to form D-methylmalonyl-CoA, which is then converted to L-methylmalonyl-CoA, and subsequently converted to succinyl-CoA through the action of the enzyme methylmalonyl-CoA mutase. Succinyl-CoA can then enter the citric acid cycle (Krebs cycle), contributing to energy production.
In the process, propionyl-CoA is carboxylated to form D-methylmalonyl-CoA, which is then converted to L-methylmalonyl-CoA, and subsequently converted to succinyl-CoA through the action of the enzyme methylmalonyl-CoA mutase. Succinyl-CoA can then enter the citric acid cycle (Krebs cycle), contributing to energy production.