Question

Which type of mutation causes cystic fibrosis?
A. substitution
B. silent
C. deletion
D. insertion

Answer 1

Cystic fibrosis is primarily caused by a deletion mutation. The most common mutation associated with cystic fibrosis is a deletion of three nucleotides in the CFTR gene, which leads to the absence of the amino acid phenylalanine at position 508 (ΔF508). Therefore, the correct answer is:

C. deletion