Question

Which type of mutation causes cystic fibrosis? (1 point)
• deletion
• insertion
• substitution
• silent

Answer 1

Cystic fibrosis is primarily caused by a **deletion** mutation. Specifically, the most common mutation involved is a deletion of three nucleotides in the CFTR gene, which results in the loss of a single phenylalanine amino acid at position 508 (referred to as ΔF508).