To rewrite the expression \(6^{-3} \cdot 6^{5}\) using a single exponent, we can use the property of exponents that states:
\[ a^m \cdot a^n = a^{m+n} \]
Applying this property to the expression:
\[ 6^{-3} \cdot 6^{5} = 6^{-3 + 5} = 6^{2} \]
So, the expression \(6^{-3} \cdot 6^{5}\) can be rewritten as:
\[ 6^{2} \]