To find the sum of the populations of the two cities in scientific notation, we first express both numbers in standard form:
- The population of the first city is \( 3.45 \times 10^6 \).
- The population of the second city is \( 1.3 \times 10^5 \).
Since \( 10^6 \) is much larger than \( 10^5 \), we need to express the second population in terms of \( 10^6 \):
\[ 1.3 \times 10^5 = 0.13 \times 10^6 \]
Now, we can add the two populations:
\[ 3.45 \times 10^6 + 0.13 \times 10^6 = (3.45 + 0.13) \times 10^6 = 3.58 \times 10^6 \]
Thus, the sum of the populations of the two cities in scientific notation is:
\[ \boxed{3.58 \times 10^6} \]