To represent the situation mathematically, we need to express the total cost of the shirts in terms of the number of shirts, \( s \).
The cost of \( s \) shirts is given by \( 16s \) (since each shirt costs $16). Demetrius can spend up to $50, which means the total cost must be less than or equal to $50.
This gives us the inequality:
\[ 16s \leq 50 \]
So the correct inequality that represents the situation is:
16s ≤ 50