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To solve for \( x \) in the equation \(-4x + 1 = 21\), follow these steps:
1. Subtract \( 1 \) from both sides:
\[
-4x + 1 - 1 = 21 - 1
\]
This simplifies to:
\[
-4x = 20
\]
2. Next, divide both sides by \(-4\):
\[
x = \frac{20}{-4}
\]
This simplifies to:
\[
x = -5
\]
So the solution is:
\[
x = -5
\]