a mutation in the hemoglobin gene results in sickle cell anemia

Answer 1

Yes, that is correct. Sickle cell anemia is caused by a specific mutation in the hemoglobin gene. This mutation leads to the production of abnormal hemoglobin, called hemoglobin S. Hemoglobin S causes red blood cells to become rigid and assume a sickle-like shape instead of their normal flexible disc shape. These sickle-shaped red blood cells can cause various health problems, such as chronic fatigue, pain crises, organ damage, and increased risk of infections.