Question

If the usual adult dose of a drug is 120 mg, what would be the dose based on BSA for a person measuring 6 ft tall and weighing 200 lb.

Answer 1

To determine the dose based on Body Surface Area (BSA), we need to calculate the BSA using the Du Bois formula:

BSA (m²) = 0.007184 × height (cm)^0.725 × weight (kg)^0.425

First, we need to convert the height from feet to centimeters:

6 feet = 6 * 30.48 cm = 182.88 cm

Next, we need to convert the weight from pounds to kilograms:

200 lb = 200 * 0.4536 kg ≈ 90.72 kg

Now we can calculate the BSA:

BSA (m²) = 0.007184 × 182.88^0.725 × 90.72^0.425

BSA (m²) ≈ 2.03 m²

The dose based on BSA can be calculated by multiplying the BSA by the usual adult dose:

Dose based on BSA = BSA * usual adult dose

Dose based on BSA ≈ 2.03 m² * 120 mg

Dose based on BSA ≈ 243.60 mg

Therefore, the dose based on BSA for a person measuring 6 ft tall and weighing 200 lb would be approximately 243.60 mg.