2 Neurotransmitter is released into the synaptic gap by

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Neurotransmitters are released into the synaptic gap (or synaptic cleft) by the presynaptic neuron. When an action potential (nerve impulse) reaches the axon terminals of the presynaptic neuron, it triggers the opening of voltage-gated calcium channels. Calcium ions (Ca²+) then flow into the neuron, which causes synaptic vesicles containing neurotransmitters to fuse with the presynaptic membrane. This fusion leads to the release of neurotransmitters into the synaptic gap, where they can bind to receptors on the postsynaptic neuron, influencing its activity.