When the stimulus intensity is increased, it primarily affects the number of synaptic vesicles released rather than the amount of neurotransmitter per vesicle. Increased stimulus intensity can lead to a greater frequency of action potentials, which results in more synaptic vesicles being released into the synaptic cleft. The amount of neurotransmitter contained in each vesicle typically remains constant. This process of increasing the number of vesicles released in response to a stronger stimulus is known as frequency-dependent synaptic transmission.
1 When the stimulus intensity is increased, what changes: the number of synaptic vesicles released or the amount of neurotransmitter per vesicle?
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