Question
glycine and lysine, have the following values of the relevant acid dissociation constants (pKa)
glycine, pKa=2.35
lysine,pKa=10.79
For an aqueous solution of glycine alone, calculate the value of pH at which the ratio of the concentration of neutral glycine zwitterions to the concentration of protonated cation is 102.
glycine, pKa=2.35
lysine,pKa=10.79
For an aqueous solution of glycine alone, calculate the value of pH at which the ratio of the concentration of neutral glycine zwitterions to the concentration of protonated cation is 102.
Answers
This tutorial may help.
http://www.chem.uiuc.edu/CLCtutorials/104/AminoAcidTitrations/SeeIt.html
I would use the Henderson-Hasselbalch equation and substitute into the log term either 1/100 or 100/1 depending upon which way you want to write it.
http://www.chem.uiuc.edu/CLCtutorials/104/AminoAcidTitrations/SeeIt.html
I would use the Henderson-Hasselbalch equation and substitute into the log term either 1/100 or 100/1 depending upon which way you want to write it.
Here is the titration curve for glycine.
https://www.google.com/search?q=titration+amino+acids&client=firefox-a&hs=ha9&rls=org.mozilla:en-US:official&channel=sb&tbm=isch&tbo=u&source=univ&sa=X&ei=jjr9U9jcKdH9yQTljIH4Dw&ved=0CCYQsAQ&biw=1024&bih=609#facrc=_&imgdii=_&imgrc=HsTtE2YEggYW1M%253A%3BEMsM7v-IV9G1fM%3Bhttp%253A%252F%252Fwww.chem.fsu.edu%252Fchemlab%252Fbch4053l%252Fcharacter%252Ftitration%252Findex_clip_image006.jpg%3Bhttp%253A%252F%252Fwww.chem.fsu.edu%252Fchemlab%252Fbch4053l%252Fcharacter%252Ftitration%252F%3B369%3B275
https://www.google.com/search?q=titration+amino+acids&client=firefox-a&hs=ha9&rls=org.mozilla:en-US:official&channel=sb&tbm=isch&tbo=u&source=univ&sa=X&ei=jjr9U9jcKdH9yQTljIH4Dw&ved=0CCYQsAQ&biw=1024&bih=609#facrc=_&imgdii=_&imgrc=HsTtE2YEggYW1M%253A%3BEMsM7v-IV9G1fM%3Bhttp%253A%252F%252Fwww.chem.fsu.edu%252Fchemlab%252Fbch4053l%252Fcharacter%252Ftitration%252Findex_clip_image006.jpg%3Bhttp%253A%252F%252Fwww.chem.fsu.edu%252Fchemlab%252Fbch4053l%252Fcharacter%252Ftitration%252F%3B369%3B275
thank you I'm looking into this albeit totally lost atm
9.78+log10(1/102)
=7.77
sounds good?
=7.77
sounds good?
Nevermind, I did it, I should be paying you for all this help ;)
I had to take other pk
2.35+log10(102)
=4.35
I had to take other pk
2.35+log10(102)
=4.35
4.35 is correct
Related Questions
Glycine is the amino acid used to make proteins
a)for each mole of glycine that burns,973.49k/mol o...
The skeletal structures of the two amino acids, glycine and lysine, are given below along with the v...
The skeletal structures of the two amino acids, glycine and lysine, are given below along with the v...
What is the sequence of amino acids formed from this gene?
Responses
A Glycine - Leucine - SerineG...