To calculate the expression \( 100000000000000000000000000000000000000000000000000000000000 + 34325253423424234324324534535656645 \times 757 \), we first need to perform the multiplication and then add the two results together.
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Multiplication:
\( 34325253423424234324324534535656645 \times 757 \)This results in:
\( = 25901627243077879257521443288677602265 \)
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Addition:
Now, we add this result to \( 100000000000000000000000000000000000000000000000000000000000 \):\[ 100000000000000000000000000000000000000000000000000000000000 + 25901627243077879257521443288677602265 \ = 100000000000000000000000000000000000000000000000000000000000 + 25901627243077879257521443288677602265 \]
Calculating the final sum:
\[ = 100000000000000000000000000000000000025901627243077879257521443288677602265 \]
So the final result is:
\[ \boxed{100000000000000000000000000000000000025901627243077879257521443288677602265} \]