The most accurate response regarding why life in the Chesapeake region was different from life in New England for early settlers is:
The climate and soil conditions of the two regions were different.
The Chesapeake region, characterized by a warmer climate and fertile soil, was more suitable for cash crops like tobacco, leading to an economy centered around agriculture and plantations. In contrast, New England's colder climate and rockier soil resulted in a more diversified economy focused on small-scale farming, fishing, and trade. These environmental differences greatly influenced the social, economic, and cultural development of each region.