Why do non-users of performance-enhancing drugs work harder and have more dedication?
Personally I think this question is biased. Just because someone uses performance enhancing drugs doens't mean they haven't worked just as hard if not harder than someone who hasn't.
The same is true for dedication. Dedication to what? Winning? Sportmanship? The answer makes a difference.
The question is obviously fishing for an anti-drug resonse, and while that's certainly admirable I don't think the question is an honest one.
Now if you rephrased the question to say "Why might some non-users have to work harder?" then the answer becomes more clear. They have to work harder to achieve the same results that others achieve by taking performance-enhancing shortcuts (i.e. cheating).