The correct responses for why the Renaissance began in Italy are:
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Italy's central location provided a good setting for commerce, so trade revived there first.
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Italy had been the center of the Roman Empire and the ancient ruins reminded people of Rome's greatness.
The statement about the Black Plague is not accurate in this context, as Italy was actually heavily affected by the Plague. Additionally, the claim that the Middle Ages had little impact on Italy is also misleading, as the Middle Ages were a significant period of transition that influenced various aspects of Italian society leading into the Renaissance.