Here are the responses to the questions provided:
Question 1: Who was responsible for setting up Santa Fe's government?
Response: Don Pedro de Peralta
Question 2: What was the main purpose of the cabildo in Santa Fe?
Response: To oversee the town's day-to-day business
Question 3: Which of the following was NOT a duty of the regidores?
Response: Designing new buildings
Question 4: What did Spanish settlers have to agree to in order to receive a land grant in New Mexico?
Response: Live on the land for 10 years and improve it
Question 5: What caused conflict between Spanish settlers and Pueblo Indians regarding the land grant system?
Response: Lack of available land
Question 6: What were acequias in Spanish settlements primarily used for?
Response: Irrigation
Question 7: Who was responsible for overseeing the annual cleaning of the main irrigation ditch, or acequia madre?
Response: Mayordomo
Question 8: What role did El Camino Real play in the colonial economy?
Response: It was the main trade route between Mexico City and Santa Fe
Question 9: How often did trade caravans typically travel from Mexico City to Santa Fe?
Response: Every year
Question 10: Native Americans killed many early missionaries in New Mexico.
Response: True
Question 11: The colonial government and Catholic Church had conflicts because they both wanted to take advantage of Native American labor.
Response: True
Feel free to ask if you need more information or clarifications on any topics!