The true statement about the relationships between the number sets is:
Whole numbers include all natural numbers and 0.
Here's a breakdown of why the others are false:
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Some irrational numbers are also integers. (False: Irrational numbers cannot be integers because integers are whole numbers that can be positive, negative, or zero, while irrational numbers cannot be expressed as a fraction of two integers.)
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Not all natural numbers are real numbers. (False: All natural numbers are indeed real numbers.)
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All rational numbers are also integers. (False: Rational numbers include fractions, and not all rational numbers are whole numbers or integers. For example, 1/2 is a rational number but not an integer.)
So, the first statement is the only true one.