The true statement is:
a. neutral mutations occur when a mutation in a DNA region results in the same sequence as the original.
Neutral mutations refer to changes in the DNA sequence that do not affect the organism’s fitness, which can occur if the mutation does not change the amino acid sequence of proteins (synonymous mutations) or if it occurs in non-coding regions. The other options describe mutations that are either harmful or beneficial, which do not fall under the classification of neutral mutations.