The statement that best describes how the Dust Bowl affected the human geography of the Great Plains in the 1930s is:
The Dust Bowl caused people to migrate from the Great Plains to other regions of the United States.
During the Dust Bowl, severe drought and poor agricultural practices led to massive dust storms, which made farming nearly impossible. As a result, many families, particularly those from Oklahoma and other affected states, left the Great Plains in search of better living conditions and job opportunities, significantly altering the region's population dynamics.