Sickle cell anemia is a genetic blood disorder characterized by the production of abnormal hemoglobin, known as hemoglobin S. This abnormal hemoglobin causes red blood cells to become rigid and shaped like a crescent or sickle, leading to various complications. These sickle-shaped cells can block blood flow in small vessels, leading to pain episodes (sickle cell crises), increased risk of infection, and anemia due to the rapid breakdown of the irregularly shaped cells. The condition is inherited in an autosomal recessive manner, meaning that a person must receive two copies of the sickle cell gene, one from each parent, to develop the disease. Management of sickle cell anemia often includes pain management, hydration, blood transfusions, and sometimes medications such as hydroxyurea.
which statement accurately describes sickle cell anemia
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