The correct statement about genetic material is:
Chromosomes are made up of genes.
Here’s a brief explanation of the other statements for clarity:
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Genes encode deoxyribonucleic acid. - This statement is misleading; genes are segments of DNA, rather than encoding for it.
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Chromatids contain chromosomes. - This is not accurate; chromatids are identical halves of a duplicated chromosome.
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Centromeres connect two chromosomes. - This is incorrect; centromeres connect two sister chromatids of the same chromosome, not two separate chromosomes.