The sentence that best conveys the central idea of the informational text is:
"I realized that if we wanted to solve a critical problem like malaria diagnosis, we needed to design a human-powered centrifuge that costs less than a cup of coffee," Prakash says in a press release.
This sentence highlights the goal of addressing a significant problem (malaria diagnosis) and emphasizes the innovative solution (a human-powered centrifuge) along with its affordable cost.